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KMID : 0358320070480070751
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Korean Journal of Urology
2007 Volume.48 No. 7 p.751 ~ p.753
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Dramatic Decline of PSA and Symptom Improvement after Estramustine Withdrawal in a Hormone-refractory Prostate Cancer Patient
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Mo Kyo-Ik
Kim Ki-Ho
Seo Young-Jin
Lee Kyung-Seop
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Abstract
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In some patients with prostate cancer and who manifest disease progression during maximal androgen blockade(MAB) therapy, discontinuation of antiandrogen treatment might result in a significant fall in the level of serum prostate-specific antigen(PSA), and this is often correlated with clinical improvement(antiandrogen withdrawal syndrome). However, a decline in the PSA level after the withdrawal of estramustine phosphate is extremely rare. We report here on a case of dramatic decline in the PSA level after withdrawal of estramustine phosphate in a patient with hormone refractory prostate cancer. (Korean J Urol 2007;48:751-753)
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KEYWORD
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Prostate cancer, Estramustine, Chemotherapy
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